Dual roles for autophagy: Degradation and secretion of Alzheimer's disease Aβ peptide

Alzheimer's disease (AD) is a neurodegenerative disease exhibiting amyloid beta (Aβ) peptide accumulation as a key characteristic. Autophagy, which is dysregulated in AD, participates in the metabolism of Aβ. Unexpectedly, we recently found that autophagy, in addition to its degradative functio...

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Detalles Bibliográficos
Autores principales: Nilsson, Per, Saido, Takaomi C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Insights & Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316186/
https://www.ncbi.nlm.nih.gov/pubmed/24711225
http://dx.doi.org/10.1002/bies.201400002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316186/
https://www.ncbi.nlm.nih.gov/pubmed/24711225
http://dx.doi.org/10.1002/bies.201400002

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