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Dual roles for autophagy: Degradation and secretion of Alzheimer's disease Aβ peptide
Alzheimer's disease (AD) is a neurodegenerative disease exhibiting amyloid beta (Aβ) peptide accumulation as a key characteristic. Autophagy, which is dysregulated in AD, participates in the metabolism of Aβ. Unexpectedly, we recently found that autophagy, in addition to its degradative functio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BlackWell Publishing Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316186/ https://www.ncbi.nlm.nih.gov/pubmed/24711225 http://dx.doi.org/10.1002/bies.201400002 |