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Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach

INTRODUCTION: Cigarette smoke contributes to a diverse range of diseases including chronic obstructive pulmonary disease (COPD), cardiovascular disorders and many cancers. There currently is a need for human challenge models, to assess the acute effects of a controlled cigarette smoke stimulus, foll...

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Detalles Bibliográficos
Autores principales: Ross, Clare L, Galloway-Phillipps, Neil, Armstrong, Paul C, Mitchell, Jane A, Warner, Timothy D, Brearley, Christopher, Ito, Mari, Tunstall, Tanushree, Elkin, Sarah, Kon, Onn Min, Hansel, Trevor T, Paul-Clark, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316420/
https://www.ncbi.nlm.nih.gov/pubmed/25631307
http://dx.doi.org/10.1136/bmjopen-2014-005750