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Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach
INTRODUCTION: Cigarette smoke contributes to a diverse range of diseases including chronic obstructive pulmonary disease (COPD), cardiovascular disorders and many cancers. There currently is a need for human challenge models, to assess the acute effects of a controlled cigarette smoke stimulus, foll...
Autores principales: | Ross, Clare L, Galloway-Phillipps, Neil, Armstrong, Paul C, Mitchell, Jane A, Warner, Timothy D, Brearley, Christopher, Ito, Mari, Tunstall, Tanushree, Elkin, Sarah, Kon, Onn Min, Hansel, Trevor T, Paul-Clark, Mark J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316420/ https://www.ncbi.nlm.nih.gov/pubmed/25631307 http://dx.doi.org/10.1136/bmjopen-2014-005750 |
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