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Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum
BACKGROUND: Endoplasmic reticulum (ER) lumenal protein thiol redox balance resists dramatic variation in unfolded protein load imposed by diverse physiological challenges including compromise in the key upstream oxidases. Lumenal calcium depletion, incurred during normal cell signaling, stands out a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316587/ https://www.ncbi.nlm.nih.gov/pubmed/25575667 http://dx.doi.org/10.1186/s12915-014-0112-2 |