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Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

BACKGROUND: Endoplasmic reticulum (ER) lumenal protein thiol redox balance resists dramatic variation in unfolded protein load imposed by diverse physiological challenges including compromise in the key upstream oxidases. Lumenal calcium depletion, incurred during normal cell signaling, stands out a...

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Detalles Bibliográficos
Autores principales: Avezov, Edward, Konno, Tasuku, Zyryanova, Alisa, Chen, Weiyue, Laine, Romain, Crespillo-Casado, Ana, Melo, Eduardo Pinho, Ushioda, Ryo, Nagata, Kazuhiro, Kaminski, Clemens F, Harding, Heather P, Ron, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316587/
https://www.ncbi.nlm.nih.gov/pubmed/25575667
http://dx.doi.org/10.1186/s12915-014-0112-2