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Age and sex differences in kidney microRNA expression during the life span of F344 rats

BACKGROUND: Growing evidence suggests that epigenetic mechanisms of gene regulation may play a role in susceptibilities to specific toxicities and adverse drug reactions. MiRNAs in particular have been shown to be important regulators in cancer and other diseases and show promise as predictive bioma...

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Detalles Bibliográficos
Autores principales: Kwekel, Joshua C, Vijay, Vikrant, Desai, Varsha G, Moland, Carrie L, Fuscoe, James C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316605/
https://www.ncbi.nlm.nih.gov/pubmed/25653823
http://dx.doi.org/10.1186/s13293-014-0019-1