Impacts of Activation of the Mitogen-Activated Protein Kinase Pathway in Pancreatic Cancer

Pancreatic cancer is characterized by constitutive activation of the mitogen-activated protein kinase (MAPK) pathway. Mutations of KRAS or BRAF and epigenetic abrogation of DUSP6 contribute synergistically to the constitutive activation of MAPK. Active MAPK induces the expression of a variety of gen...

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Detalles Bibliográficos
Autor principal: Furukawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316689/
https://www.ncbi.nlm.nih.gov/pubmed/25699241
http://dx.doi.org/10.3389/fonc.2015.00023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316689/
https://www.ncbi.nlm.nih.gov/pubmed/25699241
http://dx.doi.org/10.3389/fonc.2015.00023

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