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Optical triggered seizures using a caged 4-Aminopyridine

Animal models of epilepsy are critical not only for understanding the fundamental mechanism of epilepsy but also for testing the efficacy of new antiepileptic drugs and novel therapeutic interventions. Photorelease of caged molecules is widely used in biological research to control pharmacologic eve...

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Detalles Bibliográficos
Autores principales: Zhao, Mingrui, McGarry, Laura M., Ma, Hongtao, Harris, Samuel, Berwick, Jason, Yuste, Rafael, Schwartz, Theodore H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316705/
https://www.ncbi.nlm.nih.gov/pubmed/25698919
http://dx.doi.org/10.3389/fnins.2015.00025