Cargando…
A genomic approach to study down syndrome and cancer inverse comorbidity: untangling the chromosome 21
Down syndrome (DS), one of the most common birth defects and the most widespread genetic cause of intellectual disabilities, is caused by extra genetic material on chromosome 21 (HSA21). The increased genomic dosage of trisomy 21 is thought to be responsible for the distinct DS phenotypes, including...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316712/ https://www.ncbi.nlm.nih.gov/pubmed/25698970 http://dx.doi.org/10.3389/fphys.2015.00010 |