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A genomic approach to study down syndrome and cancer inverse comorbidity: untangling the chromosome 21

Down syndrome (DS), one of the most common birth defects and the most widespread genetic cause of intellectual disabilities, is caused by extra genetic material on chromosome 21 (HSA21). The increased genomic dosage of trisomy 21 is thought to be responsible for the distinct DS phenotypes, including...

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Detalles Bibliográficos
Autores principales: Forés-Martos, Jaume, Cervera-Vidal, Raimundo, Chirivella, Enrique, Ramos-Jarero, Alberto, Climent, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316712/
https://www.ncbi.nlm.nih.gov/pubmed/25698970
http://dx.doi.org/10.3389/fphys.2015.00010