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Dissociation of Pupillary Post-Illumination Responses from Visual Function in Confirmed OPA1 c.983A > G and c.2708_2711delTTAG Autosomal Dominant Optic Atrophy

Purpose: To test whether the melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs), as evaluated by examination of the pupillary light reflex (PLR), are preserved in genetically confirmed autosomal dominant optic atrophy (ADOA). Method: Twenty-nine patients with either...

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Detalles Bibliográficos
Autores principales: Nissen, Claus, Rönnbäck, Cecilia, Sander, Birgit, Herbst, Kristina, Milea, Dan, Larsen, Michael, Lund-Andersen, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316714/
https://www.ncbi.nlm.nih.gov/pubmed/25699009
http://dx.doi.org/10.3389/fneur.2015.00005