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Mining for viral fragments in methylation enriched sequencing data

Most next generation sequencing experiments generate more data than is usable for the experimental set up. For example, methyl-CpG binding domain (MBD) affinity purification based sequencing is often used for DNA-methylation profiling, but up to 30% of the sequenced fragments cannot be mapped unique...

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Detalles Bibliográficos
Autores principales: Mensaert, Klaas, Van Criekinge, Wim, Thas, Olivier, Schuuring, Ed, Steenbergen, Renske D.M., Wisman, G. Bea A., De Meyer, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316777/
https://www.ncbi.nlm.nih.gov/pubmed/25699076
http://dx.doi.org/10.3389/fgene.2015.00016