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Using ‘dead or dependent’ as an outcome measure in clinical trials in Parkinson's disease

BACKGROUND: Simple, robust, sensitive and clinically meaningful outcome measures are required for neuroprotective trials in Parkinson's disease (PD). We explored the feasibility of a composite binary outcome measure, ‘dead or dependent’, in such trials using data from a prospective follow-up st...

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Detalles Bibliográficos
Autores principales: McGhee, David, Parker, Alexander, Fielding, Shona, Zajicek, John, Counsell, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316847/
https://www.ncbi.nlm.nih.gov/pubmed/24854405
http://dx.doi.org/10.1136/jnnp-2014-307703