Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia

BACKGROUND: The aim of the study was to assess the role of irradiation in the expression of HIF-1α, VEGF, and P53 in human cervical carcinoma cells under a simulated hypoxia environment. MATERIAL/METHODS: The tetrazolium-based colorimetric cellular assay (MTT) and flow cytometry (FCM) were used to d...

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Detalles Bibliográficos
Autores principales: Fu, Zhichao, Chen, Dongsheng, Cheng, Huihua, Wang, Fengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316866/
https://www.ncbi.nlm.nih.gov/pubmed/25623525
http://dx.doi.org/10.12659/MSM.893265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316866/
https://www.ncbi.nlm.nih.gov/pubmed/25623525
http://dx.doi.org/10.12659/MSM.893265

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