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Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia
BACKGROUND: The aim of the study was to assess the role of irradiation in the expression of HIF-1α, VEGF, and P53 in human cervical carcinoma cells under a simulated hypoxia environment. MATERIAL/METHODS: The tetrazolium-based colorimetric cellular assay (MTT) and flow cytometry (FCM) were used to d...
Autores principales: | Fu, Zhichao, Chen, Dongsheng, Cheng, Huihua, Wang, Fengmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316866/ https://www.ncbi.nlm.nih.gov/pubmed/25623525 http://dx.doi.org/10.12659/MSM.893265 |
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