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High concentrations of mast cell chymase facilitate the transduction of the transforming growth factor-β1/Smads signaling pathway in skin fibroblasts

The aim of the present study was to investigate the effect of different concentrations of mast cell chymase on the transforming growth factor (TGF)-β1/Smad signaling pathway in skin fibroblasts. Cultured skin fibroblasts were treated with various concentrations of chymase for different time periods....

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Detalles Bibliográficos
Autores principales: DONG, XIANGLIN, ZHANG, CHUANSHAN, MA, SHAOLIN, WEN, HAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316899/
https://www.ncbi.nlm.nih.gov/pubmed/25667659
http://dx.doi.org/10.3892/etm.2015.2216