Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease

OBJECTIVE: Genome-wide association studies (GWAS) have identified genetic variants within multiple risk loci as predisposing to intestinal inflammatory diseases, including Crohn's disease, ulcerative colitis and coeliac disease. Most risk variants affect regulation of transcription, but a criti...

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Detalles Bibliográficos
Autores principales: Raine, Tim, Liu, Jimmy Z, Anderson, Carl A, Parkes, Miles, Kaser, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Intestinal Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316924/
https://www.ncbi.nlm.nih.gov/pubmed/24799394
http://dx.doi.org/10.1136/gutjnl-2013-306657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316924/
https://www.ncbi.nlm.nih.gov/pubmed/24799394
http://dx.doi.org/10.1136/gutjnl-2013-306657

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