General Strategy for the Bioorthogonal Incorporation of Strongly Absorbing, Solvation-Sensitive Infrared Probes into Proteins

[Image: see text] A high-sensitivity metal-carbonyl-based IR probe is described that can be incorporated into proteins or other biomolecules in very high yield via Click chemistry. A two-step strategy is demonstrated. First, a methionine auxotroph is used to incorporate the unnatural amino acid azid...

Descripción completa

Detalles Bibliográficos
Autores principales: Peran, Ivan, Oudenhoven, Tracey, Woys, Ann Marie, Watson, Matthew D., Zhang, Tianqi O., Carrico, Isaac, Zanni, Martin T., Raleigh, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317048/
https://www.ncbi.nlm.nih.gov/pubmed/24749542
http://dx.doi.org/10.1021/jp5008279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317048/
https://www.ncbi.nlm.nih.gov/pubmed/24749542
http://dx.doi.org/10.1021/jp5008279

Ejemplares similares