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RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts

Ninety-four percent of mammalian protein-coding exons exceed 51 nucleotides (nt) in length. The paucity of micro-exons (≤ 51 nt) suggests that their recognition and correct processing by the splicing machinery present greater challenges than for longer exons. Yet, because thousands of human genes ha...

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Detalles Bibliográficos
Autores principales: Li, Yang I., Sanchez-Pulido, Luis, Haerty, Wilfried, Ponting, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317164/
https://www.ncbi.nlm.nih.gov/pubmed/25524026
http://dx.doi.org/10.1101/gr.181990.114