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H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

In differentiated cells, aging is associated with hypermethylation of DNA regions enriched in repressive histone post-translational modifications. However, the chromatin marks associated with changes in DNA methylation in adult stem cells during lifetime are still largely unknown. Here, DNA methylat...

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Detalles Bibliográficos
Autores principales: Fernández, Agustín F., Bayón, Gustavo F., Urdinguio, Rocío G., Toraño, Estela G., García, María G., Carella, Antonella, Petrus-Reurer, Sandra, Ferrero, Cecilia, Martinez-Camblor, Pablo, Cubillo, Isabel, García-Castro, Javier, Delgado-Calle, Jesús, Pérez-Campo, Flor M., Riancho, José A., Bueno, Clara, Menéndez, Pablo, Mentink, Anouk, Mareschi, Katia, Claire, Fabian, Fagnani, Corrado, Medda, Emanuela, Toccaceli, Virgilia, Brescianini, Sonia, Moran, Sebastián, Esteller, Manel, Stolzing, Alexandra, de Boer, Jan, Nisticò, Lorenza, Stazi, Maria A., Fraga, Mario F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317171/
https://www.ncbi.nlm.nih.gov/pubmed/25271306
http://dx.doi.org/10.1101/gr.169011.113