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Muscarinic M(1) receptor and cannabinoid CB(1) receptor do not modulate paraoxon-induced seizures

One of the major signs of severe organophosphate poisoning is seizures. Previous studies have shown that both muscarinic agonist- and organophosphate-induced seizures require activation of muscarinic acetylcholine receptors in the central nervous system. Seizures induced by the muscarinic agonist pi...

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Detalles Bibliográficos
Autores principales: Kow, Rebecca L, Cheng, Eugene M, Jiang, Kelly, Le, Joshua H, Stella, Nephi, Nathanson, Neil M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317231/
https://www.ncbi.nlm.nih.gov/pubmed/25692018
http://dx.doi.org/10.1002/prp2.100