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Functional desensitization of the β(2) adrenoceptor is not dependent on agonist efficacy
Chronic treatment with β(2) adrenoceptor agonists is recommended as a first-line maintenance therapy for chronic obstructive pulmonary disease (COPD). However, a potential consequence of long-term treatment may be the loss of functional response (tachyphylaxis) over time. In this study, we have inve...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317232/ https://www.ncbi.nlm.nih.gov/pubmed/25692019 http://dx.doi.org/10.1002/prp2.101 |