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Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells

Patient data suggest that colony stimulating factor-1 (CSF1) and its receptor (CSF1R) play critical roles during breast cancer progression. We have previously shown that in human breast tumors expressing both CSF1 and CSF1R, invasion in vivo is dependent both on a paracrine interaction with tumor-as...

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Detalles Bibliográficos
Autores principales: Patsialou, Antonia, Wang, Yarong, Pignatelli, Jeanine, Chen, Xiaoming, Entenberg, David, Oktay, Maja, Condeelis, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317382/
https://www.ncbi.nlm.nih.gov/pubmed/25088194
http://dx.doi.org/10.1038/onc.2014.226