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Temporal and spatial regulation of translation in the mammalian oocyte via the mTOR–eIF4F pathway

The fully grown mammalian oocyte is transcriptionally quiescent and utilizes only transcripts synthesized and stored during early development. However, we find that an abundant RNA population is retained in the oocyte nucleus and contains specific mRNAs important for meiotic progression. Here we sho...

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Detalles Bibliográficos
Autores principales: Susor, Andrej, Jansova, Denisa, Cerna, Renata, Danylevska, Anna, Anger, Martin, Toralova, Tereza, Malik, Radek, Supolikova, Jaroslava, Cook, Matthew S., Oh, Jeong Su, Kubelka, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317492/
https://www.ncbi.nlm.nih.gov/pubmed/25629602
http://dx.doi.org/10.1038/ncomms7078