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Temporal and spatial regulation of translation in the mammalian oocyte via the mTOR–eIF4F pathway
The fully grown mammalian oocyte is transcriptionally quiescent and utilizes only transcripts synthesized and stored during early development. However, we find that an abundant RNA population is retained in the oocyte nucleus and contains specific mRNAs important for meiotic progression. Here we sho...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317492/ https://www.ncbi.nlm.nih.gov/pubmed/25629602 http://dx.doi.org/10.1038/ncomms7078 |