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Macrotene chromosomes provide insights to a new mechanism of high-order gene amplification in eukaryotes

Copy number variation of chromosomal segments is now recognized as a major source of genetic polymorphism within natural populations of eukaryotes, as well as a possible cause of genetic diseases in humans, including cancer, but its molecular bases remain incompletely understood. In the baker’s yeas...

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Detalles Bibliográficos
Autores principales: Thierry, Agnès, Khanna, Varun, Créno, Sophie, Lafontaine, Ingrid, Ma, Laurence, Bouchier, Christiane, Dujon, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317496/
https://www.ncbi.nlm.nih.gov/pubmed/25635677
http://dx.doi.org/10.1038/ncomms7154