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Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia

Conventional chemotherapy is ineffective in the majority of patients with acute myeloid leukaemia (AML), and monoclonal antibodies recognising CD33 expressed on myeloid progenitors (e.g. gemtuzumab ozogamicin (GO)) have been reported to improve outcome in patients with AML. Reports of excess toxicit...

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Detalles Bibliográficos
Autores principales: Loke, J., Khan, J. N., Wilson, J. S., Craddock, C., Wheatley, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317519/
https://www.ncbi.nlm.nih.gov/pubmed/25284166
http://dx.doi.org/10.1007/s00277-014-2218-6