Synthetic Covalently Linked Dimeric Form of H2 Relaxin Retains Native RXFP1 Activity and Has Improved In Vitro Serum Stability

Human (H2) relaxin is a two-chain peptide member of the insulin superfamily and possesses potent pleiotropic roles including regulation of connective tissue remodeling and systemic and renal vasodilation. These effects are mediated through interaction with its cognate G-protein-coupled receptor, RXF...

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Detalles Bibliográficos
Autores principales: Nair, Vinojini B., Bathgate, Ross A. D., Separovic, Frances, Samuel, Chrishan S., Hossain, Mohammed Akhter, Wade, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317577/
https://www.ncbi.nlm.nih.gov/pubmed/25685807
http://dx.doi.org/10.1155/2015/731852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317577/
https://www.ncbi.nlm.nih.gov/pubmed/25685807
http://dx.doi.org/10.1155/2015/731852

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