Intracranial Biodegradable Silica-Based Nimodipine Drug Release Implant for Treating Vasospasm in Subarachnoid Hemorrhage in an Experimental Healthy Pig and Dog Model

Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage. When administrated orally or intravenously, systemic hypotension is an undesirable side effect. Intracranial subarachnoid delivery of nimodipine during aneurysm clipping may be more eff...

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Detalles Bibliográficos
Autores principales: Koskimäki, Janne, Tarkia, Miikka, Ahtola-Sätilä, Tuula, Saloranta, Lasse, Simola, Outi, Forsback, Ari-Pekka, Laakso, Aki, Frantzén, Janek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317635/
https://www.ncbi.nlm.nih.gov/pubmed/25685803
http://dx.doi.org/10.1155/2015/715752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317635/
https://www.ncbi.nlm.nih.gov/pubmed/25685803
http://dx.doi.org/10.1155/2015/715752

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