‘Supermutators' found amongst highly levofloxacin-resistant E. coli isolates: a rapid protocol for the detection of mutation sites

Fluoroquinolone resistance is gradually acquired through several mechanisms. In particular, chromosomal mutations in the genes encoding topoisomerases II and IV and increased expression of the multidrug efflux pump AcrAB-TolC are the most common mechanisms. In this study, multiplex polymerase chain...

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Detalles Bibliográficos
Autores principales: Zayed, Ahmed Abdel-Fattah, Essam, Tamer Mohamed, Hashem, Abdel-Gawad Mohamed, El-Tayeb, Ossama Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317672/
https://www.ncbi.nlm.nih.gov/pubmed/26038761
http://dx.doi.org/10.1038/emi.2015.4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317672/
https://www.ncbi.nlm.nih.gov/pubmed/26038761
http://dx.doi.org/10.1038/emi.2015.4

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