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‘Supermutators' found amongst highly levofloxacin-resistant E. coli isolates: a rapid protocol for the detection of mutation sites
Fluoroquinolone resistance is gradually acquired through several mechanisms. In particular, chromosomal mutations in the genes encoding topoisomerases II and IV and increased expression of the multidrug efflux pump AcrAB-TolC are the most common mechanisms. In this study, multiplex polymerase chain...
Autores principales: | Zayed, Ahmed Abdel-Fattah, Essam, Tamer Mohamed, Hashem, Abdel-Gawad Mohamed, El-Tayeb, Ossama Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317672/ https://www.ncbi.nlm.nih.gov/pubmed/26038761 http://dx.doi.org/10.1038/emi.2015.4 |
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