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Characterization of 10-Hydroxygeraniol Dehydrogenase from Catharanthus roseus Reveals Cascaded Enzymatic Activity in Iridoid Biosynthesis

Catharanthus roseus [L.] is a major source of the monoterpene indole alkaloids (MIAs), which are of significant interest due to their therapeutic value. These molecules are formed through an intermediate, cis-trans-nepetalactol, a cyclized product of 10-oxogeranial. One of the key enzymes involved i...

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Detalles Bibliográficos
Autores principales: Krithika, Ramakrishnan, Srivastava, Prabhakar Lal, Rani, Bajaj, Kolet, Swati P., Chopade, Manojkumar, Soniya, Mantri, Thulasiram, Hirekodathakallu V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317706/
https://www.ncbi.nlm.nih.gov/pubmed/25651761
http://dx.doi.org/10.1038/srep08258