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MicroRNA-210 and Endoplasmic Reticulum Chaperones in the Regulation of Chemoresistance in Glioblastoma

Glioblastoma multiforme (GBM) is the commonest primary brain tumour in adults characterized by relentless recurrence due to resistance towards the standard chemotherapeutic agent temozolomide (TMZ). Prolyl 4-hydroxylase, beta polypeptide (P4HB), an endoplasmic reticulum (ER) chaperone, is known to b...

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Detalles Bibliográficos
Autores principales: Lee, Derek, Sun, Stella, Zhang, Xiao Qin, Zhang, Ping De, Ho, Amy S.W., Kiang, Karrie M.Y., Fung, Ching Fai, Lui, Wai Man, Leung, Gilberto K.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317757/
https://www.ncbi.nlm.nih.gov/pubmed/25663939
http://dx.doi.org/10.7150/jca.10765