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MKK7 mediates miR-493-dependent suppression of liver metastasis of colon cancer cells

The prognosis of advanced colon cancer patients is profoundly affected by the presence or absence of liver metastasis. miR-493 functions as a potent suppressor of liver metastasis, and low-level miR-493 expression in human primary colon cancer is associated with an elevated incidence of liver metast...

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Detalles Bibliográficos
Autores principales: Sakai, Hiroaki, Sato, Ai, Aihara, Yuki, Ikarashi, Yoshinori, Midorikawa, Yutaka, Kracht, Michael, Nakagama, Hitoshi, Okamoto, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317799/
https://www.ncbi.nlm.nih.gov/pubmed/24533778
http://dx.doi.org/10.1111/cas.12380