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Sirtuin 1 facilitates chemoresistance of pancreatic cancer cells by regulating adaptive response to chemotherapy-induced stress

Chemotherapy drugs themselves may act as stressors to induce adaptive responses to promote the chemoresistance of cancer cells. Our previous research showed that sirtuin 1 (SIRT1) was overexpressed in pancreatic cancer patients and deregulation of SIRT1 with RNAi could enhance chemosensitivity. Thus...

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Detalles Bibliográficos
Autores principales: Zhang, Jun-gang, Hong, De-fei, Zhang, Cheng-wu, Sun, Xiao-dong, Wang, Zhi-fei, Shi, Ying, Liu, Jun-wei, Shen, Guo-liang, Zhang, Yuan-biao, Cheng, Jian, Wang, Chun-you, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317803/
https://www.ncbi.nlm.nih.gov/pubmed/24484175
http://dx.doi.org/10.1111/cas.12364