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Sirtuin 1 facilitates chemoresistance of pancreatic cancer cells by regulating adaptive response to chemotherapy-induced stress

Chemotherapy drugs themselves may act as stressors to induce adaptive responses to promote the chemoresistance of cancer cells. Our previous research showed that sirtuin 1 (SIRT1) was overexpressed in pancreatic cancer patients and deregulation of SIRT1 with RNAi could enhance chemosensitivity. Thus...

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Detalles Bibliográficos
Autores principales:	Zhang, Jun-gang, Hong, De-fei, Zhang, Cheng-wu, Sun, Xiao-dong, Wang, Zhi-fei, Shi, Ying, Liu, Jun-wei, Shen, Guo-liang, Zhang, Yuan-biao, Cheng, Jian, Wang, Chun-you, Zhao, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317803/ https://www.ncbi.nlm.nih.gov/pubmed/24484175 http://dx.doi.org/10.1111/cas.12364

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