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Suppression of Tregs by anti-glucocorticoid induced TNF receptor antibody enhances the antitumor immunity of interferon-α gene therapy for pancreatic cancer

We have reported that interferon (IFN)-α can attack cancer cells by multiple antitumor mechanisms including the induction of direct cancer cell death and the enhancement of an immune response in several pancreatic cancer models. However, an immunotolerant microenvironment in the tumors is often resp...

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Detalles Bibliográficos
Autores principales: Aida, Kouichirou, Miyakawa, Reina, Suzuki, Koji, Narumi, Kenta, Udagawa, Takeshi, Yamamoto, Yuki, Chikaraishi, Tatsuya, Yoshida, Teruhiko, Aoki, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317823/
https://www.ncbi.nlm.nih.gov/pubmed/24289533
http://dx.doi.org/10.1111/cas.12332