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Suppression of Tregs by anti-glucocorticoid induced TNF receptor antibody enhances the antitumor immunity of interferon-α gene therapy for pancreatic cancer
We have reported that interferon (IFN)-α can attack cancer cells by multiple antitumor mechanisms including the induction of direct cancer cell death and the enhancement of an immune response in several pancreatic cancer models. However, an immunotolerant microenvironment in the tumors is often resp...
Autores principales: | Aida, Kouichirou, Miyakawa, Reina, Suzuki, Koji, Narumi, Kenta, Udagawa, Takeshi, Yamamoto, Yuki, Chikaraishi, Tatsuya, Yoshida, Teruhiko, Aoki, Kazunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317823/ https://www.ncbi.nlm.nih.gov/pubmed/24289533 http://dx.doi.org/10.1111/cas.12332 |
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