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Apurinic/apyrimidinic endonuclease 1 induced upregulation of fibroblast growth factor 2 and its receptor 3 induces angiogenesis in human osteosarcoma cells

Tumor angiogenesis contributes to inferior prognosis in osteosarcoma. Apurinic/apyrimidinic endonuclease 1 (APE1) and fibroblast growth factor 2 (FGF2) and its receptor 3 (FGFR3) signaling pathway plays an important role in the angiogenic process. In this study we observed that high expression of AP...

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Detalles Bibliográficos
Autores principales: Ren, Tao, Qing, Yi, Dai, Nan, Li, Mengxia, Qian, Chengyuan, Yang, Yuxin, Cheng, Yi, Li, Zheng, Zhang, Shiheng, Zhong, Zhaoyang, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317824/
https://www.ncbi.nlm.nih.gov/pubmed/24329908
http://dx.doi.org/10.1111/cas.12334