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Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines

Effective molecular target drugs that improve therapeutic efficacy with fewer adverse effects for esophageal cancer are highly anticipated. Poly(ADP-ribose) polymerase (PARP) inhibitors have been proposed as low-toxicity agents to treat double strand break (DSB)-repair defective tumors. Several find...

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Detalles Bibliográficos
Autores principales: Nasuno, Tomomitsu, Mimaki, Sachiyo, Okamoto, Makito, Esumi, Hiroyasu, Tsuchihara, Katsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317825/
https://www.ncbi.nlm.nih.gov/pubmed/24219164
http://dx.doi.org/10.1111/cas.12322