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Amino-terminal fragments of laminin γ2 chain retract vascular endothelial cells and increase vascular permeability

Laminin γ2 (Lmγ2) chain, a subunit of laminin-332, is a typical molecular marker of invading cancer cells, and its expression correlates with poor prognosis of cancer patients. It was previously found that forced expression of Lmγ2 in cancer cells promotes their invasive growth in nude mice. However...

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Detalles Bibliográficos
Autores principales: Sato, Hiroki, Oyanagi, Jun, Komiya, Eriko, Ogawa, Takashi, Higashi, Shouichi, Miyazaki, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317827/
https://www.ncbi.nlm.nih.gov/pubmed/24238220
http://dx.doi.org/10.1111/cas.12323