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Bone resorption facilitates osteoblastic bone metastatic colonization by cooperation of insulin-like growth factor and hypoxia
Bone metastasis is a multistep process that includes cancer cell dissemination, colonization, and metastatic growth. Furthermore, this process involves complex, reciprocal interactions between cancer cells and the bone microenvironment. Bone resorption is known to be involved in both osteolytic and...
Autores principales: | Kuchimaru, Takahiro, Hoshino, Takuya, Aikawa, Tomoya, Yasuda, Hisataka, Kobayashi, Tatsuya, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317828/ https://www.ncbi.nlm.nih.gov/pubmed/24597654 http://dx.doi.org/10.1111/cas.12391 |
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