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Antitumor effect of fibrin glue containing temozolomide against malignant glioma

Temozolomide (TMZ), used to treat glioblastoma and malignant glioma, induces autophagy, apoptosis and senescence in cancer cells. We investigated fibrin glue (FG) as a drug delivery system for the local administration of high-concentration TMZ aimed at preventing glioma recurrence. Our high-power li...

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Detalles Bibliográficos
Autores principales: Anai, Shigeo, Hide, Takuichiro, Takezaki, Tatsuya, Kuroda, Jun-ichiro, Shinojima, Naoki, Makino, Keishi, Nakamura, Hideo, Yano, Shigetoshi, Kuratsu, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317836/
https://www.ncbi.nlm.nih.gov/pubmed/24673719
http://dx.doi.org/10.1111/cas.12397