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Antitumor effect of fibrin glue containing temozolomide against malignant glioma
Temozolomide (TMZ), used to treat glioblastoma and malignant glioma, induces autophagy, apoptosis and senescence in cancer cells. We investigated fibrin glue (FG) as a drug delivery system for the local administration of high-concentration TMZ aimed at preventing glioma recurrence. Our high-power li...
Autores principales: | Anai, Shigeo, Hide, Takuichiro, Takezaki, Tatsuya, Kuroda, Jun-ichiro, Shinojima, Naoki, Makino, Keishi, Nakamura, Hideo, Yano, Shigetoshi, Kuratsu, Jun-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317836/ https://www.ncbi.nlm.nih.gov/pubmed/24673719 http://dx.doi.org/10.1111/cas.12397 |
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