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An inhibition of p62/SQSTM1 caused autophagic cell death of several human carcinoma cells

p62/SQSTM1 (p62) is a multifunctional protein implicated in several signal transduction pathways and selectively degraded by autophagy, a process for lysosomal degradation of both protein and organelle. p62 was also recently reported to be overexpressed in various malignancies and its inhibition to...

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Detalles Bibliográficos
Autores principales: Nihira, Kaito, Miki, Yasuhiro, Ono, Katsuhiko, Suzuki, Takashi, Sasano, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317843/
https://www.ncbi.nlm.nih.gov/pubmed/24618016
http://dx.doi.org/10.1111/cas.12396