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Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment

Indoleamine 2,3-dioxygenase (IDO) is a tryptophan-catabolizing enzyme that has immunoregulatory functions. Our prior study showed that tumoral IDO overexpression is involved in disease progression and impaired patient survival in human ovarian cancer, although its mechanism remains unclear. The purp...

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Detalles Bibliográficos
Autores principales: Tanizaki, Yuko, Kobayashi, Aya, Toujima, Saori, Shiro, Michihisa, Mizoguchi, Mika, Mabuchi, Yasushi, Yagi, Shigetaka, Minami, Sawako, Takikawa, Osamu, Ino, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317851/
https://www.ncbi.nlm.nih.gov/pubmed/24826982
http://dx.doi.org/10.1111/cas.12445