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Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR–STAT3/microRNA143 pathway

Cancer cells preferentially metabolize glucose through aerobic glycolysis, a phenomenon known as the Warburg effect. Emerging evidence has shown that long non-coding RNAs (lncRNAs) act as key regulators of multiple cancers. However, it remains largely unexplored whether and how lncRNA regulates gluc...

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Detalles Bibliográficos
Autores principales: Li, Zhengkun, Li, Xu, Wu, Shouzhen, Xue, Mei, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317864/
https://www.ncbi.nlm.nih.gov/pubmed/24890811
http://dx.doi.org/10.1111/cas.12461