In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe

Membrane type-1 matrix metalloproteinase (MT1-MMP) is a protease activating MMP-2 that mediates cleavage of extracellular matrix components and plays pivotal roles in tumor migration, invasion and metastasis. Because in vivo noninvasive imaging of MT1-MMP would be useful for tumor diagnosis, we deve...

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Detalles Bibliográficos
Autores principales: Shimizu, Yoichi, Temma, Takashi, Hara, Isao, Makino, Akira, Kondo, Naoya, Ozeki, Ei-ichi, Ono, Masahiro, Saji, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317866/
https://www.ncbi.nlm.nih.gov/pubmed/24863849
http://dx.doi.org/10.1111/cas.12457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317866/
https://www.ncbi.nlm.nih.gov/pubmed/24863849
http://dx.doi.org/10.1111/cas.12457

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