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In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe
Membrane type-1 matrix metalloproteinase (MT1-MMP) is a protease activating MMP-2 that mediates cleavage of extracellular matrix components and plays pivotal roles in tumor migration, invasion and metastasis. Because in vivo noninvasive imaging of MT1-MMP would be useful for tumor diagnosis, we deve...
Autores principales: | Shimizu, Yoichi, Temma, Takashi, Hara, Isao, Makino, Akira, Kondo, Naoya, Ozeki, Ei-ichi, Ono, Masahiro, Saji, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317866/ https://www.ncbi.nlm.nih.gov/pubmed/24863849 http://dx.doi.org/10.1111/cas.12457 |
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