Loss of gastric gland mucin-specific O-glycan is associated with progression of differentiated-type adenocarcinoma of the stomach

Gastric gland mucin secreted from the lower portion of the gastric mucosa contains unique O-linked oligosaccharides having terminal α1,4-linked N-acetylglucosamine (αGlcNAc) residues largely attached to a MUC6 scaffold. Previously, we generated A4gnt-deficient mice, which totally lack αGlcNAc, and s...

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Detalles Bibliográficos
Autores principales: Shiratsu, Kazuo, Higuchi, Kayoko, Nakayama, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317868/
https://www.ncbi.nlm.nih.gov/pubmed/24138592
http://dx.doi.org/10.1111/cas.12305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317868/
https://www.ncbi.nlm.nih.gov/pubmed/24138592
http://dx.doi.org/10.1111/cas.12305

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