In vitro and ex vivo evaluation of a multi-epitope heparinase vaccine for various malignancies

Previous studies have indicated that heparanase (Hpa) might represent a candidate universal tumor-associated antigen. However, vaccine therapy targeting only one cytotoxic T lymphocyte (CTL) epitope is suboptimal in preventing cancer. In the present study, we designed heparanase multi-epitope vaccin...

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Detalles Bibliográficos
Autores principales: Tang, Xu-Dong, Guo, Shu-Liang, Wang, Guo-Zhen, Li, Ning, Wu, Yu-Yun, Fang, Dian-Chun, Fan, Ya-Han, Yang, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317872/
https://www.ncbi.nlm.nih.gov/pubmed/24152338
http://dx.doi.org/10.1111/cas.12308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317872/
https://www.ncbi.nlm.nih.gov/pubmed/24152338
http://dx.doi.org/10.1111/cas.12308

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